CALCIUM D3 NYCOMED
CU GUST DE PORTOCALĂ
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">comprimate
masticabilemso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">DENUMIREA
COMERCIALĂmso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
Calcium D3 Nycomed
cu gust de portocală
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">DCI-ul
substanţelor activecolor:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
Calcii
carbonasmso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
Cholecalciferolum"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">COMPOZIŢIA"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">1 comprimat
masticabil conţine:mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">substanţe
active: mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">carbonat de calciu-1250 mg
(echivalent cu 500 mg calciu elementar), colecalciferol (vitamina D3)-5,0
mcg (200 UI) sub formă de concentrat de colecalciferol 2 mg;"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">excipienţi: "Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">sorbitol (E420), aromă granulată
de portocală sau de izmă bună (isomalt (E953), aromă de portocală sau izmă
bună, mono- şi digliceride a acizilor graşi), povidonă, stearat de magneziu,
aspartam.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">FORMA
FARMACEUTICĂmso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Comprimate
masticabile.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">DESCRIEREA
MEDICAMENTULUI
mso-fareast-font-family:"Times New Roman";mso-font-kerning:0pt;mso-ligatures:
none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Comprimate
masticabile de formă rotundă, biconvexe, de culoare albă, cu gust de portocală
sau mintă. Pot fi prezente incluziuni.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">GRUPA
FARMACOTERAPEUTICĂ şi codul ATCcolor:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Calciu,
combinaţii cu vitamină D şi/sau alte minerale, A12AX"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">PROPRIETĂŢILE
FARMACOLOGICE
mso-fareast-font-family:"Times New Roman";mso-font-kerning:0pt;mso-ligatures:
none;mso-ansi-language:EN-US;mso-fareast-language:RU">
color:#4A4E52;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">Proprietăţi farmacodinamice"Times New Roman";color:#4A4E52;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Vitamina D3facilitează"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU"> absorbţia calciului în
intestin. Administrarea calciului şi vitaminei D3 împiedică
creşterea sintezei hormonului paratiroidian, care cauzează deficienţa de calciu
şi este un stimulator al resorbţiei osoase."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Proprietăţi
farmacocineticecolor:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Calciu"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Absorbţie"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">De regulă,
circa 30% din doza administrată se absoarbe din tractul gastrointestinal."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Distribuţie şi
metabolizaremso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">99% de calciu
în organism este concentrată în structura dură a oaselor şi dinţilor. 1% se
află în lichidul intra- şi extracelular. Circa 50% din cantitatea plasmatică
totală de calciu se află sub formă ionizată fiziologic activă, din ea circa 10%
în complex cu citrat, fosfat sau alţi anioni, restul 40% sunt legaţi cu
proteine, în primul rând cu albumina.
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Eliminare"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Calciul se
elimină prin masele fecale, urină şi sudoraţie. Eliminarea renală depinde de
filtrarea glomerulară şi reabsorbţia tubulară a calciului."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Vitamina D3"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Absorbţie"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Vitamina D3 se
absoarbe uşor în intestinul subţire.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Distribuţie şi
metabolizaremso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Colecalciferolul
şi metaboliţii lui circulă în sânge legaţi cu globulina specifică."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Colecalciferolul
se metabolizează în ficat prin hidroxilare până la 25-hidroxicolecalciferol.
Apoi în rinichi se transformă în forma sa activă 1,25- hidroxicolecalciferol.
1,25-hidroxicolecalciferol este metabolitul, responsabil de creşterea
absorbţiei calciului. Vitamina D3 nemetabolizată se depozitează
în ţesutului adipos şi muscular.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Eliminare"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Vitamina D3 se
elimină prin intestin şi rinichi.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">INDICAŢII
TERAPEUTICEmso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
Profilaxia şi
tratamentul deficitului de calciu şi/sau al vitaminei "Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">D."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
Profilaxia şi
tratamentul complex al osteoporozei la pacienţii cu risc înalt al deficitului
de calciu şi/sau al vitaminei color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">D.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">DOZE ŞI MOD DE
ADMINISTRARE
mso-fareast-font-family:"Times New Roman";mso-font-kerning:0pt;mso-ligatures:
none;mso-ansi-language:EN-US;mso-fareast-language:RU">
Calcium D3 Nycomed
cu gust de portocală/mintă se administrează intern. Comprimatul poate fi
mestecat sau se va ţine în cavitatea bucală până la dizolvare completă şi se va
administra în timpul mesei.
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Tratamentul
adjuvant al osteoporozeicolor:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Câte 1
comprimat de 2-3 ori pe zi.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Deficit de
calciu şi/sau al vitaminei Dcolor:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Adulţi "Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">- câte 1 comprimat de 1-3 ori pe
zi.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Copii "Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">- câte 1 comprimat de 1-2 ori pe
zi.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Grupe speciale
de pacienţimso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Afectarea
funcţiei hepaticecolor:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
Nu este
necesară ajustarea doze preparatului.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Afectarea
funcţiei renalemso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Calcium D3 Nycomed
cu gust de portocală/mintănu se va administra în insuficienţă renală severă."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">REACŢII
ADVERSEmso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Reacţiile
adverse sunt prezentate utilizând următoarea convenţie privind frecvenţa:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">-mai puţin
frecvente ≥1/1000 şi <1/100;color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">-rare ≥1/10000
şi <1/1000;mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">-foarte rare
(<1/10000).mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Tulburări
metabolice şi de nutriţie:color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">mai puţin frecvente-hipercalciemie şi hipercalciurie."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Tulburări
gastrointestinale: color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">rare-constipaţii, meteorism, greaţă, dureri în
abdomen, diaree; foarte rare - dispepsie."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Afecţiuni
cutanate şi ale ţesutului subcutanat:color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">foarte rare-prurit, erupţii cutanate, urticarie."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">CONTRAINDICAŢII
mso-fareast-font-family:"Times New Roman";mso-font-kerning:0pt;mso-ligatures:
none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">-Hipersensibilitate la substanţele
active sau la oricare din excipienţi;color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">-maladii
şi/sau condiţii, care cauzează hipercalciemie şi/sau hipercalciurie;"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">-nefrolitiază;"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
-"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">hipervitaminoza D."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">SUPRADOZAJ"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
Supradozajul
poate cauza hipervitaminoză şi hipercalciemie."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
Simptomele hipercalciemiei:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">anorexie, sete, greţuri, vomă, constipaţii,
dureri abdominale, color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">slăbiciune musculară, fatigabilitate, tulburări
psihice, polidipsie,mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:
RU"> poliurie,mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
dureri de
oase, nefrocalcinoză, litiază renală, în cazuri severe-aritmii. Hipercalciemia
severă poate cauza comă şi moarte.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
La
administrarea îndelungată a dozelor înalte-afectare renală ireversibilă,
calcinoza ţesuturilor moi.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
Tratament: sistarea administrării
preparatului, de asemenea a diureticelor tiazidice şi glicozidelor cardiace şi
se va adresa la medic.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
Se recomandă
lavaj gastric, consum abundent de lichide, administrarea diureticelor de ansă
(de ex. furosemid), glucocorticosteroizilor, calcitoninei, bifosfonaţilor."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
În cazul
dezvoltării simptomelor clinice de supradozaj se recomandă controlul
concentraţiei plasmatice a electroliţilor, funcţiei renale şi diurezei."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">În cazuri
severe se recomandă determinarea tensiunii venoase centrale şi controlului ECG."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">ATENŢIONĂRI ŞI
PRECAUŢII SPECIALE DE UTILIZAREcolor:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">La
administrare îndelungată se recomandă controlul nivelului plasmatic de calciu
şi creatinină. Supravegherea este foarte importantă la vârstnici în tratamentul
concomitent cu glicozide cardiace şi diuretice şi la pacienţii cu predispoziţie
la formare a calculilor renali. În caz de hipercalciemie sau simptome de
afectare a funcţiei renale se recomandă reducerea dozei sau sistarea
tratamentului.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Vitamina D se
va administra cu precauţie la pacienţii cu insuficienţă renală. În acest caz se
recomandă controlul nivelului plasmatic de calciu şi fosfaţi. De aceea trebuie
de avut în vedere riscul dezvoltării calcinozei ţesuturilor moi. La pacienţii
cu insuficienţă renală severă, vitamina D sub formă de colecalciferol nu se
metabolizează normal, de aceea se recomandă utilizarea altor forme de vitamină
D.
mso-fareast-font-family:"Times New Roman";mso-font-kerning:0pt;mso-ligatures:
none;mso-ansi-language:EN-US;mso-fareast-language:RU">
Calcium D3 Nycomed
cu gust de portocală/mintă se va administra cu precauţie la pacienţii cu
sarcoidoză, deoarece există risc crescut de creştere a metabolismului vitaminei
D în forma sa activă. La aceşti pacienţi se va monitoriza sistematic nivelul de
calciu în ser şi urină.
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Preparatul se
va administra cu precauţie la pacienţii imobilizaţi cu osteoporoză din cauza
riscului de dezvoltare a hipercalciemiei."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">La
administrarea altor preparate care conţin vitamina D trebuie de avut în vedere
conţinutul de vitamină D (200 UI) în Calcium D3 Nycomedcu gust
de portocală/mintă. Administrarea dozelor suplimentare de calciu şi vitamină D
se va efectua sub supravegherea medicului. În aceste cazuri se recomandă
monitorizarea frecventă a nivelului seric al calciului şi excreţia urinară a
calciului.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Sindromul
lapte-alcalin (sindromul Burnett), care se manifestă prin hipercalciemie,
alcaloză şi insuficienţă renală, poate să se dezvolte la administrarea
cantităţilor înalte de calciu cu alcaline."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Administrarea
concomitentă cu antibioticele din grupul tetraciclinei sau chinolone, de
regulă, nu se recomandă sau se va indica cu precauţie."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Calcium D3 Nycomed
cu gust de portocală/mintă conţine aspartam, care în organism se transformă în
fenilalanină. De aceea, preparatul nu se va administra la pacienţii cu
fenilcetonurie.mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Preparatul
conţine sorbitol, isomalt, zaharoză, de aceea preparatul nu se va administra
pacienţilor cu intoleranţa ereditară de fructoză, malabsorbţie de
glucoză-galactoză sau insuficienţă de zaharază-izomaltază."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Administrarea
în sarcină şi perioada de alăptare"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Preparatul se
va administra cu precauţie în sarcină şi perioada de alăptare."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">În perioada de
sarcină doza nictemerală nu va depăşi 1500 mg de calciu şi 600 UI vitamina D3.
Calciul şi vitamina D3 se excretă în laptele matern, de aceea
trebuie de ţinut cont de aportul suplimentar al vitaminei D3 din
alte surse.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Influenţa
asupra capacităţii de a conduce vehicule sau de a folosi utilaje"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Nu există date
privind influenţa Calcium D3 Nycomed cu gust de
portocală/mintă asupra capacităţii de a conduce vehicule sau de a folosi
utilaje.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">INTERACŢIUNI
CU ALTE MEDICAMENTE, ALTE TIPURI DE INTERACŢIUNI"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Diureticele
tiazidice reduc excreţia urinară a calciului. Datorită creşterii riscului de
hipercalciemie, în tratamentul combinat se recomandă de controlat concentraţia
plasmatică de calciu.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Carbonatul de
calciu poate interfera absorbţia preparatelor din grupul tetraciclinelor. De aceea, "Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">antibioticele din grupul tetraciclinei se vor administra
cu 2 ore până la sau peste 4-6 ore după "Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">Calcium D3 Nycomed
cu gust de portocală/mintă.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Hipercalciemia
potenţează efectele toxice ale glicozidelor cardiace la administrarea
concomitentă cu preparatele de calciu şi vitamina D3. Este necesară
monitorizarea ECG şi nivelului plasmatic de calciu."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
Intervalul
dintre administrarea preparatului color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">Calcium D3 Nycomed cu gust de
portocală/mintă şi bifosfonaţilor trebuie să fie de cel puţin 1 oră, pentru a evita
reducerea absorbţiei ultimelor.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
Calciul reduce
eficacitatea levotiroxinei, reducând absorbţia acesteia. Intervalul dintre
administrarea preparatului color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">Calcium D3 Nycomed cu gust de
portocală/mintă şi levotiroxină trebuie să fie de cel puţin 4 ore."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Preparatele de
calciu încetinesc absorbţia antibioticelor din grupul chinolonelor. De aceea, "Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:RO;mso-fareast-language:RU">antibioticele din grupul chinolonelor se vor administra cu
2 ore până sau peste 6 ore după color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:RO;
mso-fareast-language:RU">Calcium D3 Nycomed cu gust de
portocală/mintă.mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">PREZENTARE,
AMBALAJmso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Comprimate
masticabile cu gust de portocală, câte 50 sau 100 în flacon."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Comprimate
masticabile cu gust de mintă, câte 30 în flacon."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Câte 1 flacon
împreună cu instrucţiunea pentru administrare în cutie de carton."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">PĂSTRARE"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
A se păstra la
temperatura sub 25 ºC.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">A nu se lăsa
la îndemâna şi vederea copiilor.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">TERMEN DE
VALABILITATEmso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:
RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">3 ani."Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">A nu se
utiliza după data de expirare indicată pe ambalaj.
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">STATUTUL LEGAL"Times New Roman";color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;
mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Fără
prescripţie medicală.color:#292B2C;mso-font-kerning:0pt;mso-ligatures:none;mso-ansi-language:EN-US;
mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">NUMELE ŞI
ADRESA PRODUCĂTORULUI
mso-fareast-font-family:"Times New Roman";mso-font-kerning:0pt;mso-ligatures:
none;mso-ansi-language:EN-US;mso-fareast-language:RU">
mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:RO;mso-fareast-language:RU">Takeda Nycomed
AS Norvegia.mso-fareast-font-family:"Times New Roman";color:#292B2C;mso-font-kerning:0pt;
mso-ligatures:none;mso-ansi-language:EN-US;mso-fareast-language:RU">
